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Drugs of Abuse Confirmation/Quantitation - Opiates - Meconium
Test Code3594
Alias/See Also
Meconium
Preferred Specimen
Meconium. All meconium (blackish material) excreted until milk/formula based stool (yellow-green) appears.
Minimum Volume
1 g per each separate confirmation required (equivalent to a cube 1/2 inch on a side) at 20-25°C. (Min: 0.5 g or 1/4 inch cube)
Transport Temperature
1 g per each separate confirmation required (equivalent to a cube 1/2 inch on a side) at 20-25°C. (Min: 0.5 g or 1/4 inch cube)
Specimen Stability
Ambient: 1 week; Refrigerated: 3 months; Frozen: 1 year
Methodology
Liquid Chromatography-Tandem Mass Spectrometry
Setup Schedule
Sun-Sat
Report Available
1-4 days
Clinical Significance
Drugs Covered: codeine, dihydrocodeine, morphine, 6-acetylmorphine, hydrocodone, hydromorphone, oxycodone and oxymorphone. Positive cutoff: 2 ng/gMeconium begins to form between the 12th and 16th week of gestation. Meconium drug testing can detect maternal drug use during the last 4 to 5 months of pregnancy. A negative result does not exclude the possibility that a mother used drugs during pregnancy. Detection of drug use depends on the quantity and quality of the specimen tested as well as the pattern and frequency of drug(s) used by mother. The concentration value must be greater than or equal to the cutoff to be reported as positive. Although not likely, the presence of drugs administered during labor and delivery may be detected in meconium. Interpretive questions should be directed to the laboratory. For medical purposes only; not valid for forensic use.
