Hemoglobin A[1c]

Test Code

2910

Alias/See Also

hemoglobin A1c; Glycohemoglobin; HbA1c; A1C; Glycated Hemoglobin

Preferred Specimen

One 5 mL lavender (EDTA) or pink (K2EDTA).

Minimum Volume

5 mL whole blood in original lavender draw tube at 2-8°C. (Min: 1 mL)

Transport Temperature

5 mL whole blood in original lavender draw tube at 2-8°C. (Min: 1 mL)

Specimen Stability

Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Methodology
High Performance Liquid Chromatography/Boronate Affinity

Setup Schedule

Sun-Sat

Report Available

1-2 days

Clinical Significance

Hemoglobin A1c values of 5.7-6.4 percent indicate an increased risk for developing diabetes mellitus. Hemoglobin A1c values greater than or equal to 6.5 percent are diagnostic of diabetes mellitus. Diagnosis should be confirmed by repeating the Hb A1c test.This boronate affinity Hb A1c method provides accurate analytical results in the presence of nearly all hemoglobin variants. Hb F higher than 10 percent of total Hb may yield falsely low results. Conditions that shorten red cell survival, such as the presence of unstable hemoglobins like Hb SS, Hb CC, and Hb SC, or other causes of hemolytic anemia may yield falsely low results. Iron deficiency anemia may yield falsely high results.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.