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C-Reactive Protein, High Sensitivity
Test Code2160
Alias/See Also
HSCRP; CRP High Sensitivity; High Sensitivity, CRP
Preferred Specimen
Serum separator tube. Also acceptable: Plasma separator tube, lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).
Minimum Volume
Refrigerated.
Instructions
Allow specimen to clot completely at room temperature. Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.3 mL)
Transport Temperature
Refrigerated.
Specimen Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 months; Frozen: 1 year
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolyzed specimens.
Methodology
Quantitative Immunoturbidimetry
Setup Schedule
Sun-Sat
Report Available
Within 24 hours
Clinical Significance
Not recommended for general cardiovascular disease risk assessment in asymptomatic adults. May aid in CVD risk stratification in specific populations. Patients with higher hs-CRP concentrations are more likely to develop stroke, myocardial infarction, and severe peripheral vascular disease. CRP is a nonspecific marker of inflammation and a variety of conditions other than atherosclerosis may cause elevated concentrations. If the first result is greater than 3.0 mg/L, recommend repeating test at least 2 weeks later in a metabolically stable state, free of infection or acute illness. The lower of the two results should be used to determine the patient's risk.Significantly decreased CRP values may result in specimens from patients treated with carboxypenicillins.
