ZAP70, IHC without Interpretation

Test Code

90242

CPT Codes
88342

Preferred Specimen

Formalin-fixed, paraffin-embedded tissue block

Other Acceptable Specimens

Minimum: 3 unstained, positively charged slides

Transport Container

IHC Specimen Transport Kit

Transport Temperature

Room temperature

Specimen Stability

Room temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Unacceptable

Methodology
Immunohistochemistry

Setup Schedule

Set up: Mon-Fri; Report available: Next day

Clinical Significance

The T-cell kinase ZAP70 is anomalously expressed in the
more aggressive, pregerminal center subset of B-cell
chronic lymphocytic leukemia and small lymphocytic
lymphoma. Expression of ZAP70 by immunohistochemistry is
well-correlated with overexpression of ZAP70 by
transcript analysis or immunohistochemistry.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.