A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #

p27, IHC without Interpretation

Test Code
90226


CPT Codes
88342

Preferred Specimen
Formalin-fixed paraffin-embedded tissue block submitted in an IHC specimen transport kit


Other Acceptable Specimens
3 unstained, (+) positively charged slides


Transport Temperature
Room temperature


Specimen Stability
Room temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Unacceptable


Methodology
Immunohistochemistry (IHC)

Setup Schedule
Set up: Mon-Fri; Report available: Next day


Clinical Significance
Dysregulation of the nuclear cycle regulator p27 is implicated in the development and progression of oral squamous cell carcinoma (including by HPV). Underexpression of p27 is an adverse prognostic marker in breast, lung, prostate, and thyroid carcinomas. It is also deleted/underexpressed in some high-grade hematopoietic tumors.


Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.