JC Virus DNA, Ultrasensitive, Quantitative, Real-Time PCR, CSF

Test Code

18939

CPT Codes
87799

Preferred Specimen

1.2 mL frozen CSF collected in a sterile leak-proof container

Minimum Volume

0.6 mL

Transport Temperature

Frozen

Specimen Stability

Room temperature: 48 hours
Refrigerated: 14 days
Frozen: 30 days

Methodology
Real-Time Polymerase Chain Reaction (PCR)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Mon-Sat; Report available: 2-4 days

Reference Range

JC Virus DNA, Ultra, QN PCR	Not detected (IU/mL)
JC Virus DNA, Ultra, QN PCR	Not detected (Log IU/mL)

Clinical Significance

JC polyoma virus (JCV) is the cause of progressive multifocal leukoencephalopathy (PML), a demyelinating neurologic disease of immunocompromised patients and patients on certain medications. This test detects and quantifies JCV in cerebrospinal fluid (CSF). Detection of the virus in CSF may indicate infection. This is a quantitative molecular test with a linear range of 50-1,000,000 IU/mL.

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.