FACTOR VII ACTIVITY

Test Code

800599

CPT Codes
85230

Preferred Specimen

plasma

Minimum Volume

1ml

Instructions

"If the patient's hematocrit exceeds 55%, the volume of citrate in the collection tube must be adjusted. Refer to Coagulation Collection Procedures for directions.
"

Transport Container

"Blue-top (sodium citrate) tube
"

Transport Temperature

frozen

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

"

Gross hemolysis; clotted specimen; frozen specimen thawed in transit; improper labeling
"

Methodology
"Factor VII activity is determined utilizing a prothrombin time (PT)-based one-stage clotting time assay. Factor VII-depleted plasma is used as the substrate, and the clotting time with the patient plasma is compared to the clotting time of normal pooled plasma. "

Limitations

"Artifactual elevations in factor VII can occur as the result of cold activation of factor VII in the collection tube prior to analysis.6 Refrigerating or placing the on ice for an extended period prior to freezing the plasma can result in the conversion of factor VII to activated factor VIIa.6
"

Reference Range

"

Day 1

52-88

Day 3

67-107

1 mo to 1 y

83-160

1-5 y

72-150

6-10 y

70-156

11-16 y

69-200

Adults

50-150

"

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.