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Actin (smooth Muscle) Antibody (ASMA)
Test Code6643
Alias/See Also
antiactin, ASMA, smooth muscle antibodies
CPT Codes
83516
Preferred Specimen
Serum
Minimum Volume
0.3 ml
Transport Container
Red-top tube or gel-barrier tube
Transport Temperature
Room Temperature
Specimen Stability
14 Days. Freeze/thaw cycles stable x3
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis; lipemia; gross bacterial contamination; heat-treated specimen; specimen with preservative added
Methodology
Enzyme-linked immunosorbent assay (ELISA)
Limitations
Antiactin antibodies have been reported at low levels in 3% to 18% of sera from the general healthy population. The presence of immune complexes in the patient's sample may produce false positives in this assay. Not all smooth muscle positive samples will have actin antibodies.
Reference Range
Negative=0-19, weak positive=20-30, moderate to strong positive >30