CHROMOSOME, LEUKEMIA/LYMPHOMA

Message

"Include tentative diagnosis/treatment on the test request form. This is necessary for proper culturing and result interpretation. Please direct any questions regarding this test to customer service at 800-345-4363.
"

Test Code

52001

CPT Codes
88237; 88264; 88280(x2)

Includes

"Short-term and, in some cases, long-term ß-mitogen culturing of specimens, chromosome preparation, and analysis of 20 metaphases; multiple karyotypes prepared, including all abnormal clones
"

Preferred Specimen

"Bone marrow, blood (>4% blasts required - see Collection), lymph node, spleen, bone core, or effusion
"

Minimum Volume

"

2 mL bone marrow, 3 mL peripheral blood, or 0.5-1 cm3 tissue biopsy
"

Transport Container

"Bone marrow or peripheral blood in pediatric green-top (heparin) tube; lymph node, spleen, bone core, CSF, or effusion in lymph node transport bottle
"

Transport Temperature

room temp

Methodology
" Short-term cell culture; synchronization; chromosome harvest; G-banding; analysis (20 metaphases) and karyotyping; long-term ß-mitogen cultures in some B-cell leukemias "

Limitations

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Availability of immature blasts; excessive amounts of sodium heparin or use of lithium heparin or EDTA will inhibit growth of cell culture.
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The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.