Nation Jewish Health Hyper IgE Syndrome Panel

Test Code

678

CPT Codes
81405x1, 88271x55, 88291x1

Includes

DOCK8, SPINK5, STAT3, TYK2

Preferred Specimen

2-5 mL Blood

Instructions

forms required: requsition form, informed consent, test info sheet

Transport Container

Lavender Top Tube

Methodology
Exon Array CGH, Next-gen Sequencing

Report Available

8-10 weeks

Clinical Significance

Hyper-IgE syndromes caused by mutations in the STAT3 and DOCK8 genes are characterized by eczema, sinopulmonary infections and greatly elevated serum IgE. Elevated IgE has also been observed in an individual with TYK2 deficiency and in individuals with Netherton syndrome, a disorder associated with mutations in the SPINK5 gene.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.