INFERTILITY-MALE, Y CHROM DNA

Message

"The patient's name, age, and relevant clinical history should be included on the request form.
"

Test Code

512053

Alias/See Also

"AZF Testing Reflex
Azoöspermia Reflex
Normal Chromosomes Reflex to Y Deletion
Oligospermia Reflex
Y Deletion Reflex
"

CPT Codes
81479

Includes

"Detection of the following long-arm Y chromosome loci: DAZ, SPGY, DYS209, DYS224, DYS273, DYS275
"

Preferred Specimen

"Whole blood 7 mL (2 mL pediatric)
"

Minimum Volume

3 mL

Transport Container

"Lavender-top (EDTA) tube or yellow-top (ACD) tube
"

Transport Temperature

room temp

Specimen Stability

Do not freeze

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

"Frozen specimen; hemolysis; quantity not sufficient for analysis; improper container
"

Methodology
"Polymerase chain reaction (PCR) to detect the presence/absence of long-arm Y chromosome loci (DAZ, SPGY, DYS209, DYS224, DYS273, DYS275). "

Limitations

"Results of this test are for investigational purposes only. The performance characteristics of this assay have been determined by LabCorp. The result should not be used as a diagnostic procedure without confirmation of the diagnosis by another medically established diagnostic product or procedure.
"

Clinical Significance

"Determine the genetic basis for oligospermia or azoöspermia. Azoöspermia may also be associated with cystic fibrosis mutations, primarily the 5T allele.
"

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.