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DPD 5-Fluorouracil Toxicity
MessageLabCorp
Test Code
511176
Alias/See Also
"DPD 5-Fluorouracil Toxicity
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CPT Codes
81400
Preferred Specimen
"Whole blood or LabCorp buccal swab kit (buccal swab collection kit contains instructions for use of a buccal swab)
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Minimum Volume
"3 mL whole blood or two buccal swabs
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Other Acceptable Specimens
" LabCorp buccal swab kit
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Instructions
"Maintain specimen at room temperature or refrigerate at 4°C.
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Transport Container
"Lavender-top (EDTA) tube, yellow-top (ACD) tube
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Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
"Frozen specimen; hemolysis; quantity not sufficient for analysis; improper container; one buccal swab; wet buccal swab
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Methodology
"Polymerase chain reaction (PCR); restriction enzyme digestion; gel electrophoresis "
Limitations
"This procedure will only detect the presence of the wild type or mutant allele for the DPD IVS14+1G>A mutation.
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