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Labcorp #510252 p53 Oncology Fluorescence in situ Hybridization (FISH)
Test Code510252
Alias/See Also
"• FISH
• Leukemia FISH
• Lymphoma FISH
"
• Leukemia FISH
• Lymphoma FISH
"
CPT Codes
88271; 88275
Preferred Specimen
Fixed-cell pellet from a cytogenetic analysis, slides with metaphases and/or interphase nuclei, or bone marrow touch prep slides. Blood, bone marrow, cerebrospinal fluid (CSF), FNA are also acceptable.
Minimum Volume
Fixed-cell pellet from a cytogenetic analysis, two slides, 5 mL blood (adult), 1 mL blood (pediatric), or 1 mL bone marrow
Instructions
Transport to the testing lab at room temperature; use a cool pack or LabCorp transport kit. Do not allow sample to freeze. Sample must arrive in the laboratory within 72 hours of collection.
Transport Container
Green-top (sodium heparin) tube; pediatric Vacutainer® is optimal or lavender-top (EDTA) tube
Specimen Stability
Maintain specimen at room temperature.
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Broken or dirty slides; excessive cellular debris or stained slides; decalcified bone cores; frozen specimen
Methodology
Fluorescence in situ hybridization (FISH)
Clinical Significance
Confirmation/identification of leukemia/lymphoma-related alterations; leukemia/lymphoma monitoring of residual disease, transplants, and indolent clones (see list or call lab for probe availability)
