| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
FERRITIN, SERUM
Test Code4598
CPT Codes
82728
Preferred Specimen
"Serum
"
"
Minimum Volume
0.3
Transport Container
"Red-top tube or gel-barrier tube
"
"
Transport Temperature
"Refrigerate.
"
"
Specimen Stability
5 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
"Citrate plasma specimen; improper labeling
"
"
Methodology
"Electrochemiluminescence immunoassay (ECLIA) "
Limitations
"
Ferritin is an acute-phase reactant and thus may be increased in people with inflammation, liver disease, chronic infection, autoimmune disorders, and some types of cancer. Ferritin measurement is of limited usefulness during pregnancy because it diminishes late in pregnancy, even when bone marrow iron is present.
In patients receiving therapy with high biotin doses (ie, >5 mg/day), no sample should be taken until at least eight hours after the last biotin administration.1 As with all tests containing monoclonal mouse antibodies, erroneous findings may be obtained from samples taken from patients who have been treated with monoclonal mouse antibodies or have received them for diagnostic purposes.1 In rare cases, interference due to extremely high titers of antibodies to streptavidin and ruthenium can occur.1
"
Ferritin is an acute-phase reactant and thus may be increased in people with inflammation, liver disease, chronic infection, autoimmune disorders, and some types of cancer. Ferritin measurement is of limited usefulness during pregnancy because it diminishes late in pregnancy, even when bone marrow iron is present.
In patients receiving therapy with high biotin doses (ie, >5 mg/day), no sample should be taken until at least eight hours after the last biotin administration.1 As with all tests containing monoclonal mouse antibodies, erroneous findings may be obtained from samples taken from patients who have been treated with monoclonal mouse antibodies or have received them for diagnostic purposes.1 In rare cases, interference due to extremely high titers of antibodies to streptavidin and ruthenium can occur.1
"
Reference Range
"
0-5 m
13-273
12-219
6-12 m
12-95
12-110
1-5 y
12-64
12-71
6-11 y
16-77
15-79
12-19 y
16-124
15-77
Adult
30-400
15-150
"
0-5 m
13-273
12-219
6-12 m
12-95
12-110
1-5 y
12-64
12-71
6-11 y
16-77
15-79
12-19 y
16-124
15-77
Adult
30-400
15-150
"
Clinical Significance
"Diagnose hypochromic, microcytic anemias. Decreased in iron deficiency anemia and increased in iron overload. Ferritin levels correlate with and are useful in evaluation of total body storage iron. In hemochromatosis, both ferritin and iron saturation are increased. Ferritin levels in hemochromatosis may be >1000 ng/mL.
"
"
