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Arup Lab 2004221 Anti-NMDA Receptor IgG
MessageIf NMDA antibody IgG is positive, then an NMDA antibody IgG titer is reported. Additional charges apply.
Test Code
2004221
Alias/See Also
NMDA IGG
CPT Codes
86255; if reflexed, add 86256
Includes
2004222 N-methyl-D-Aspartate Receptor Ab, Serum
Preferred Specimen
Serum 1 mL
Minimum Volume
0.15 mL
Instructions
Separate serum from cells ASAP or within 2 hours of collection
Transport Container
ARUP Standard Transport Tube
Transport Temperature
Refrigerated.
Specimen Stability
Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
CSF or plasma. Contaminated, hemolyzed, or severely lipemic specimens
Methodology
Semi-Quantitative Indirect Fluorescent Antibody
Setup Schedule
Tue, Fri
Report Available
1-5 days
Reference Range
<1:10
Clinical Significance
Anti-NMDA receptor IgG antibody is found in a subset of patients with autoimmune limbic encephalitis and may occur with or without associated tumor. Decreasing antibody levels may be associated with therapeutic response; therefore, clinical correlation must be strongly considered. A negative test result does not rule out a diagnosis of autoimmune limbic encephalitis.
