Bacterial Vaginosis (Sialidase) and Vaginal Yeast Culture

Message

"Bradshaw CS, Morton AN, Garland SM, et al, “Evaluation of a Point-of-Care Test, BVBlue, and Clinical Laboratory Criteria for Diagnosis of Bacterial Vaginosis,” J Clin Microbiol, 2005, 43(3):1304-8.PubMed 15750100

"

Test Code

182709

Alias/See Also

BV (Sialidase) and Vaginal Yeast (Culture)

CPT Codes
87102; 87905

Preferred Specimen

"Vaginal fluid
"

Minimum Volume

"Swab
"

Instructions

"Using transport swabs provided, collect vaginal fluid sample by contacting the lower one-third of the vaginal wall, rotating for 10 to 20 seconds to absorb fluid. Immediately place the swabs into the transport tubes.
"

Transport Container

"Copan double swab in Amies liquid medium
"

Transport Temperature

"Maintain specimen at room temperature or refrigerate (2°C to 30°C) for as long as 72 hours.
"

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

"Specimen collected or transport other than previously described
"

Methodology
"BV (sialidase) activity: chromogenic enzyme activity test; vaginal yeast culture: culture "

Limitations

"BV (sialidase) activity: Collecting specimens from the cervix should be avoided because (a) it might increase the risk to OB patients, and (b) cervical sialidase activity is usually higher than vaginal sialidase activity. Do not collect specimens from patients who have (a) used a vaginal cream or ointment product, (b) douched, or (c) used spermicides, vaginal lubricants, or feminine sprays within 72 hours of testing. If insufficient sample is collected or collected from a patient undergoing antimicrobial therapy, the test may give a false-negative result.
"

Clinical Significance

"BV (sialidase) activity: Enzyme activity test for use in the detection of vaginal fluid specimens for sialidase activity, an enzyme produced by bacteria associated with bacterial vaginitis, including Bacteroides spp, Prevotella spp, and Mobiluncus spp, and some G vaginalis. In a recent study, Bradshaw et al demonstrated the test to be 88% sensitive and 95% specific.

Vaginal yeast culture: Detect yeast in vaginal fluid
"

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.