| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
CELIAC DISEASE HLA DQ ASSOC.
Message"If you have questions, please telephone HLA customer service at 800-533-1037 for assistance in selecting the appropriate HLA test for the patient.
"
"
Test Code
167082
Alias/See Also
"HLA DQ2
HLA DQ8
HLA Typing (DQ2, DQ8)
"
HLA DQ8
HLA Typing (DQ2, DQ8)
"
CPT Codes
81377; 81383
Preferred Specimen
"Whole blood or buccal swabs
7 mL or four buccal swabs
"
7 mL or four buccal swabs
"
Minimum Volume
"3 mL or four buccal swabs
"
"
Transport Container
"Lavender-top (EDTA) tube or four buccal swabs in a sealed envelope (buccal swab kit). If submitting buccal swabs, please use the kit provided by LabCorp. To obtain the buccal swab kit or to discuss other specimen types, please telephone 800-533-1037.
"
"
Transport Temperature
Room temp
Specimen Stability
"Maintain specimen at room temperature. Protect from extreme heat or cold
"
"
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
"Incorrect specimen container (tube type); yellow-top (ACD) tube
"
"
Methodology
"Polymerase chain reaction (PCR)/sequence-specific oligonucleotide probes (Luminex®) "
Limitations
"Even with appropriate precautions, an occasional specimen may not be satisfactory for testing. In such cases, fresh specimens should be collected for retesting. More than 95% of celiac disease patients are positive for either DQ2 or DQ8; however, these antigens may also be present in individuals who do not have celiac disease.
"
"
Clinical Significance
"HLA DQ2 and HLA DQ8 are statistically associated with celiac disease and are sometimes used as tests in support of that diagnosis.
"
"
