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B PERTUSSIS IGM AB
Test Code161752
CPT Codes
86615
Preferred Specimen
"Serum
0.4 mL
"
0.4 mL
"
Minimum Volume
"0.2 mL
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"
Transport Container
"Red-top tube or gel-barrier tube
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"
Transport Temperature
"Refrigerate
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"
Specimen Stability
"Refrigerate
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"
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
"Hemolysis; lipemia; gross bacterial contamination
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"
Methodology
"Enzyme-linked immunosorbent assay (ELISA) "
Reference Range
"Negative: <1.0 index
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Clinical Significance
"Establish evidence of early/acute infection with Bordetella pertussis, the causative agent of whooping cough
Patients with acute infection develop IgG, IgM, and IgA antibodies to fimbrial agglutinogens, and IgM and IgA antibodies are probably diagnostic. Following vaccination, IgG and IgM antibodies can be demonstrated. The presence of specific IgM in a single sample may indicate an acute infection and should be considered suggestive of recent infection or a presumptive diagnosis of a supporting clinical presentation.
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Patients with acute infection develop IgG, IgM, and IgA antibodies to fimbrial agglutinogens, and IgM and IgA antibodies are probably diagnostic. Following vaccination, IgG and IgM antibodies can be demonstrated. The presence of specific IgM in a single sample may indicate an acute infection and should be considered suggestive of recent infection or a presumptive diagnosis of a supporting clinical presentation.
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