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B PERTUSSIS IGG AB
Test Code161745
CPT Codes
86615
Preferred Specimen
"
Serum
0.4 mL
"
Serum
0.4 mL
"
Minimum Volume
"0.2 mL
"
"
Transport Container
"Red-top tube or gel-barrier tube
"
"
Transport Temperature
refrigerated
Specimen Stability
refrigerated
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
"Hemolysis; lipemia; gross bacterial contamination
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"
Methodology
"Enzyme-linked immunosorbent assay (ELISA) "
Reference Range
"Negative: <10 U/mL
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"
Clinical Significance
"Establish evidence of infection/exposure to Bordetella pertussis, the causative agent of whooping cough
Patients with acute infection develop IgG, IgM, and IgA antibodies to fimbrial agglutinogens, and IgM and IgA antibodies are probably diagnostic. Following vaccination, IgG and IgM antibodies can be demonstrated. IgG antibodies can only be used to diagnose acute infection when paired sera are available and a rise in antibody level can be demonstrated
"
Patients with acute infection develop IgG, IgM, and IgA antibodies to fimbrial agglutinogens, and IgM and IgA antibodies are probably diagnostic. Following vaccination, IgG and IgM antibodies can be demonstrated. IgG antibodies can only be used to diagnose acute infection when paired sera are available and a rise in antibody level can be demonstrated
"
