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C-Peptide, 24-Hour Urine
Test Code003236
CPT Codes
84681
Preferred Specimen
Urine (24-hour), frozen
Minimum Volume
"1 mL
"
"
Other Acceptable Specimens
10 mL
Instructions
Instruct the patient to void at 8 AM and discard the specimen. Then collect all urine including the final specimen voided at the end of the 24-hour collection period (ie, 8 AM the next morning) in a 24-hour urine collection container. pH should be 4-7.
Transport Container
Plastic urine container
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
pH <3 or pH >8
Methodology
Electrochemiluminescence immunoassay (ECLIA
Limitations
In patients receiving therapy with high biotin doses (ie, >5 mg/day), no sample should be taken until at least eight hours after the last biotin administration.4
Reference Range
17.2-181.0 µg/24 hours
