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Thiopurine Metabolites
Test Code503800
CPT Codes
82542
Preferred Specimen
Whole blood
Minimum Volume
1mL
Instructions
Collect blood in lavender-top (EDTA) tube only. Gently invert to mix. Submit whole blood refrigerated. Do not separate specimen. Do not freeze.
Transport Container
Lavender-top (EDTA) tube
Transport Temperature
Refrigerate
Specimen Stability
Room temp: 1 day: Refrigerate: 14 days; Frozen: UNSTABLE
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Frozen specimen, not EDTA whole blood
Methodology
Whole blood washing and red blood cell harvesting/counting. Liquid chromatography/tandem mass spectrometry (LC/MS-MS) after acidic hydrolysis