ZAP70, IHC without Interpretation

Test Code
90242


CPT Codes
88342

Preferred Specimen
Formalin-fixed, paraffin-embedded tissue block submitted in an IHC specimen transport kit


Other Acceptable Specimens
3 unstained, (+) positively charged slides


Transport Temperature
Room temperature


Specimen Stability
Room temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Unacceptable


Methodology
Immunohistochemistry (IHC)

Setup Schedule
Set up: Mon-Fri; Report available: Next day


Clinical Significance
The T-cell kinase ZAP70 is anomalously expressed in the more aggressive, pregerminal center subset of B-cell chronic lymphocytic leukemia and small lymphocytic lymphoma. Expression of ZAP70 by immunohistochemistry is well-correlated with overexpression of ZAP70 by transcript analysis or immunohistochemistry.


Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.