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Sjogren's Antibodies (SS-A, SS-B)
Test CodeQ7832
Preferred Specimen
2 mL serum (1.0 mL minimum)
Minimum Volume
0.5 mL
Transport Container
No additive (red-top) or SST
Transport Temperature
Refrigerate
Specimen Stability
Room temperature: 4 days
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Grossly icteric
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Mon-Sat; Report available: 1-3 days
Clinical Significance
Sjögren's antibodies (SS-B) is detected in approximately 15% of patients with Sjögren's Syndrome. Sjögren's antibody (SS-B) is present only if Sjögren's antibody (SS-A) is also detected. The presence of both antibodies (SS-A and SS-B) strengthen the diagnosis of Sjögren's Syndrome and conveys prognostic information.