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Sex Hormone Binding Globulin (SHBG)
Test CodeQ30740
Preferred Specimen
0.7 mL serum
Minimum Volume
0.5 mL
Instructions
Specify age and sex on test request form.
Transport Container
SST
Transport Temperature
Room Temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 28 days
Refrigerated: 7 days
Frozen: 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis, plasma
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Daily; Report available: 2-3 days
Clinical Significance
Testosterone, dihydrotestosterone and estrogens circulate in serum bound to Sex Hormone Binding Globulin (SHBG). SHBG concentrations are increased in pregnancy, hyperthyroidism, cirrhosis, oral estrogen administration and by certain drugs. Concentrations are decreased by testosterone, hypothyroidism, Cushings syndrome, acromegaly and obesity.
