|
|
| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Cardiolipin Antibody (IgG)
Test CodeQ4662
Preferred Specimen
1 mL plasma (0.5 mL minimum)
Alternate specimen: 1 mL serum (0.5 mL minimum)
Alternate specimen: 1 mL serum (0.5 mL minimum)
Minimum Volume
0.5 mL
Other Acceptable Specimens
1 mL serum
Transport Container
3.2% sodium citrate (light blue-top)
Alternate specimen: SST
Alternate specimen: SST
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 5 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Tues-Sat; Report available: 3-5 days
Clinical Significance
Cardiolipin antibodies (CA) are seen in a subgroup of patients with autoimmune disorders, particularly Systemic Lupus Erythematosus (SLE), who are at risk for vascular thrombosis, thrombocytopenia, cerebral infarct and/or recurrent spontaneous abortion. Elevations of CA associated with increased risk have also been seen in idiopathic thrombocytopenic purpura, rheumatoid and psoriatic arthritis, and primary Sjögren's syndrome.
