Bupropion and Metabolite 8592

Test Code

CPT Codes

Bupropion and Hydroxybupropion

Preferred Specimen
1 mL frozen serum collected in a red-top tube (no gel)

Minimum Volume
0.4 mL

Other Acceptable Specimens
Frozen plasma collected in: EDTA (lavender-top) tube

Collect as trough prior to next dose. Collect serum and remove from cells

Transport Container
Plastic screw-cap vial

Transport Temperature

Specimen Stability
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature • Received refrigerated • Gel barrier/Serum Separator Tube (SST®)

Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: Tues, Thurs, Sat p.m.; Report available: Next day

Reference Range
Bupropion 50-100 ng/mL
Hydroxybupropion 600-2000 ng/mL

Clinical Significance
Bupropion is an antidepressant for treating mental depression. Monitoring its level is important to optimize therapy, to avoid toxicity and to assure compliance.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.