A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #

Mitogen Ag Induce Lym Pan91978

Test Code
MITOANT


Alias/See Also
MITOANT


CPT Codes
86353

Includes
Phytohemagglutinin (PHA)-induced Lymphocyte Proliferation
Concanavalin A (Con A)-induced Lymphocyte Proliferation
Pokeweed Mitogen (PWM)-induced Lymphocyte Proliferation
Candida-induced Lymphocyte Proliferation
Tetanus-induced Lymphocyte Proliferation
Tuberculin PPD-induced Lymphocyte Proliferation


Preferred Specimen
20 mL whole blood collected in a sodium heparin (green-top) tube


Minimum Volume
1


Instructions
Spec draw Mon-Thur before noon. Send to lab immediately Four green top tubes


Transport Container
DK GREEN


Transport Temperature
T


Specimen Stability
Room temperature: 48 hours
Refrigerated: Unacceptable
Frozen: Unacceptable


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Received refrigerated • Received frozen • Clotted specimens • Samples collected in lithium heparin tubes


Methodology
Cell Culture (CC) • Scintillation Counter

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: Tues-Fri; Report available: 15 days


Reference Range
See Laboratory Report


Clinical Significance
Measurement of human lymphocytes' proliferative responses to various stimuli is a fundamental technique used to assess their biological status and functions. Mitogens, such as plant lectins phytohemagglutinin (PHA), concanavalin A (Con A) and pokeweed mitogen (PWM), are able to nonspecifically stimulate lymphocyte proliferation and used to evaluate patient immune responsiveness. Lymphocyte proliferation response to antigens, such as Candida, tetanus toxoid and tuberculin purified protein derivative (PPD), are evaluated as a function of memory in cell-mediated immunity.


Performing Laboratory
Quest Diagnostics Nichols Inst San Juan Capistrano
33608 Ortega Highway
San Juan Capistrano, CA 92675



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.