|
|
| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Gonadotropin Releasing Hormone 9190
Test CodeGONAREL
Alias/See Also
GONAREL
CPT Codes
83727
Preferred Specimen
3 mL frozen plasma collected in an EDTA (lavender-top) tube
Patient Preparation
Patient should not be on any hormonal treatment for 2 days
Minimum Volume
1
Instructions
Draw one lavender (EDTA) and send plasma frozen.
Transport Container
LAV
Transport Temperature
F
Specimen Stability
Room temperature: Unacceptable
Refrigerated: 6 hours
Frozen: 90 days
Refrigerated: 6 hours
Frozen: 90 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Serum
Methodology
Enzyme Linked Immunosorbent Assay (ELISA) • Extraction
FDA Status
This test was developed and its analytical performance characteristics have been determined by Pan Laboratories. This assay has been validated pursuant to the CLIA regulations. It has not been cleared or approved by the U.S. Food and Drug Administration.
Setup Schedule
Set up: Wed, Fri; Report available: 2-7 days
Reference Range
0-10.0 pg/mL
Clinical Significance
Gonadotropin releasing hormone (Gn RH or LH RH) is a ten amino acid peptide produced mainly in the hypothalamus. It stimulates pituitary for the production of LH and FSH. The stimulation is predominantly on LH secretion and hence it is called LH RH. LH and FSH stimulate the production of gonadal hormones (e.g testosterone in males and estrogens in females). These steroid hormones have a feedback control on Gn RH secretion. Increased secretion occurs during puberty leading to the raise in concentration of LH and FSH for the stimulation of gonads. LH RH levels are high when there is secondary hypogonadism with decreased level of LH and FSH. LH RH levels are low in tertiary (hypothalamic) hypogonadism and also individuals with high stress levels with elevated dopamine and prolactin. LH RH and its agonists are routinely used in IVF settings to induce ovulation.
Performing Laboratory
Pan Laboratories, LLC
15375 Barranca Pkw, E101
Irvine, CA 92618
