Gonadotropin Releasing Hormone 9190

Test Code
GONAREL

Alias/See Also
GONAREL

CPT Codes
83727

Preferred Specimen
3 mL plasma collected in an EDTA (lavender-top) tube

Patient Preparation
Patients should not be on any hormonal treatment for 2 days (48 hours).

Minimum Volume
1

Other Acceptable Specimens
Serum collected in a red-top tube (no gel)

Instructions
Draw one lavender (EDTA) and send plasma frozen.

Transport Container
LAV

Transport Temperature
F

Specimen Stability
Room temperature: Not stable
Refrigerated: 6 hours
Frozen: 90 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature • Received refrigerated • Gross hemolysis

Methodology
Enzyme Linked Immunosorbent Assay (ELISA) • Extraction

FDA Status
This test was developed and its analytical performance characteristics have been determined by Pan Laboratories. This assay has been validated pursuant to the CLIA regulations. It has not been cleared or approved by the U.S. Food and Drug Administration.

Setup Schedule
Set up: Tues a.m.; Report available: 3-8 days

Reference Range
0-10.0 pg/mL

Clinical Significance
Gonadotropin releasing hormone (Gn RH or LH RH) is a ten amino acid peptide produced mainly in the hypothalamus. It stimulates pituitary for the production of LH and FSH. The stimulation is predominantly on LH secretion and hence it is called LH RH. LH and FSH stimulate the production of gonadal hormones (e.g testosterone in males and estrogens in females). These steroid hormones have a feedback control on Gn RH secretion. Increased secretion occurs during puberty leading to the raise in concentration of LH and FSH for the stimulation of gonads. LH RH levels are high when there is secondary hypogonadism with decreased level of LH and FSH. LH RH levels are low in tertiary (hypothalamic) hypogonadism and also individuals with high stress levels with elevated dopamine and prolactin. LH RH and its agonists are routinely used in IVF settings to induce ovulation.

Performing Laboratory
Pan Laboratories, LLC
15375 Barranca Pkw, E101
Irvine, CA 92618



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.