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Diazepam and Metabolite 90853
Test CodeDIAZEP
Alias/See Also
DIAZEP
CPT Codes
80346
Includes
Diazepam, Nordiazepam, Diazepam and Nordiazepam
Preferred Specimen
2 mL serum collected in a red-top tube (no gel)
Minimum Volume
1
Instructions
Collect specimen immediately before dose and send serum frozen
Transport Container
RED
Transport Temperature
F
Specimen Stability
Room temperature: Unacceptable
Refrigerated: 5 days
Frozen: 14 days
Refrigerated: 5 days
Frozen: 14 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum Separator Tube (SST®)
Methodology
Calculation (CALC) • Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Tues, Thurs, Sat; Report available: 3-5 days
Reference Range
Diazepam | See Laboratory Report |
Nordiazepam | See Laboratory Report |
Diazepam and Nordiazepam
Therapeutic | 100-1500 ng/mL |
Potentially toxic | >3000 ng/mL |
Clinical Significance
Therapeutic drug monitoring of anxiolytic drug. Nordiazepam is the active metabolite of the parent drug. Elimination half-life is 20-90 hours.
Performing Laboratory
Quest Diagnostics Nichols Institute Valencia
27027 Tourney Road
Valencia, CA 91355-5386