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| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Thyroid CA Monitoring 90814
Test CodeTHYCANCER
Alias/See Also
THYCANCER
CPT Codes
86800;84432
Includes
If Thyroglobulin Ab is negative then Thyroglobulin is tested on Beckmen Coulter. If Thyroglobulin Ab is positive then Thyroglobulin is tested by LC/MS/MS
Preferred Specimen
3 mL serum
Minimum Volume
1
Instructions
Draw SST and send at room temperature
Transport Container
SST
Transport Temperature
T
Specimen Stability
Room temperature: 6 days
Refrigerated: 7 days
Frozen: 28 days
Refrigerated: 7 days
Frozen: 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Lipemia • Plasma • Icteric
Methodology
Immunoenzymatic
Setup Schedule
Set up: Sun, Tues-Sat; Report available: 7-8 days
Reference Range
| Thyroglobulin Antibody | ≤1 IU/mL |
| Thyroglobulin | Athyrotic: <0.1 ng/mL |
| Thyroglobulin, LC/MS/MS | Athyrotic: <0.4 ng/mL |
Clinical Significance
Thyroglobulin measurements are most useful in the postoperative monitoring of patients with papillary, follicular, and Hurthle cell carcinomas. However, approximately 20% of individuals develop autoantibodies to thyroglobulin. Since these antibodies interfere with immunoassay measurement of thyroglobulin, it is necessary to determine the presence or absence of antibodies before measuring thyroglobulin. This panel provides a sensitive method for determination of thyroglobulin autoantibodies, with subsequent measurement of thyroglobulin by either a sensitive immunoassay (Tg Ab negative samples) or LCMSMS (Tg Ab positive samples). The mass spectrometry assay has no interference from autoantibodies.
Performing Laboratory
| Quest Diagnostics Nichols Institute |
| 14225 Newbrook Drive |
| Chantilly, VA 20153 |
