|
|
| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Neutrophil Function Oxid37523
Test CodeNEUTOXID
Alias/See Also
NEUTOXID
CPT Codes
82657
Preferred Specimen
3 mL whole blood collected in a sodium heparin (green-top) tube
--and--
2nd specimen (Control): 3 mL whole blood in sodium heparin (green-top) tube
--and--
2nd specimen (Control): 3 mL whole blood in sodium heparin (green-top) tube
Minimum Volume
2
Instructions
Must be drawn before noon. Mon-Thurs Send to Lab Immeditatly Draw two green top tube.
Transport Container
DK GREEN
Transport Temperature
T
Specimen Stability
Room temperature: 72 hours
Refrigerated: Unacceptable
Frozen: Unacceptable
Refrigerated: Unacceptable
Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Lipemia • Icterus • Clotted specimens • Refrigerated and frozen specimens
Methodology
Flow Cytometry (FC)
FDA Status
The test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulation and is used for clinical purposes.
Setup Schedule
Set up: Daily; Report available: 3-4 days
Reference Range
%Oxidation Pos Neutrophils
| 24 Hours | ≥93% |
| 48 Hours | ≥83% |
| 72 Hours | ≥82% |
Clinical Significance
This assay measures the capability of neutrophils (PMN) to undergo oxidative metabolism to produce superoxide anion and hydrogen peroxide, as detected by oxidation of dihydrorhodamine (DHR). Patients with chronic granulomatous disease (CGD) are unable to oxidize DHR due to defects in oxidative capacity slowly decreases as the specimen age (hours post collection) increases. It is thus important that the reference range value appropriate for the specimen age be utilized when assessing the reported results.
Performing Laboratory
| Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
| 33608 Ortega Highway |
| San Juan Capistrano, CA 92675-2042 |
