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Mycophenol 16662
Test CodeMYCOPHENOL
Alias/See Also
MYCOPHENOL
CPT Codes
80180
Includes
Mycophenolic Acid and MPA Glucuronide
Preferred Specimen
1 mL serum collected in a red-top tube (no gel)
Patient Preparation
Optimum time to collect sample: 1/2 hour to 1 hour before next dose (trough) at steady-state (3-5 days after treatment with oral doses)
Minimum Volume
1
Other Acceptable Specimens
Plasma collected in: Sodium heparin (green-top) tube or EDTA (lavender-top) tube
Instructions
Collect one red top (no gel) Send serum refrigerated
Transport Container
RED
Transport Temperature
R
Specimen Stability
Room temperature: 72 hours
Refrigerated: 14 days
Frozen: 60 days
Refrigerated: 14 days
Frozen: 60 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Lipemia • Improperly labeled specimens • Specimens left at room temperature >72 hours • Gel barrier/serum separator tube (SST)
Methodology
Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Mon-Sat a.m.; Report available: 2 days
Reference Range
Mycophenolic Acid | 1.0-3.5 mcg/mL |
MPA Glucuronide | 35.0-100.0 mcg/mL |
Clinical Significance
Mycophenolic acid is an immunosuppressant used in tissue transplants. It prevents graft rejection by the host's immune system. It is very important to monitor its level. Too little of this drug will cause graft rejectoin, while too much will lead to infection. Monitoring its level is essential to optimize therapeutic effects, avoid toxicity, and assure compliance.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153