|
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Cyclic Citru Peptid Antibody 11173
Test CodeCCP IGG
Alias/See Also
CCP IGG
CPT Codes
86200
Preferred Specimen
1 mL serum
Minimum Volume
1
Instructions
Draw one SST and send serum refrigerated
Transport Container
SST
Transport Temperature
R
Specimen Stability
Room temperature: 4 days
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Gross lipemia • Plasma
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Tues-Sat a.m.; Report available: Next day
Limitations
The presence of immune complexes may cause false-positive results due to increased non-specific binding.
Reference Range
Negative | <20 Units | ||||
Weak positive | 20-39 Units | ||||
Moderate positive | 40-59 Units | ||||
Strong positive | >59 Units |
Clinical Significance
A synthetic circular peptide containing citrulline called CCP IgG (cyclic citrullinated peptide) has been found to be better at discriminating Rheumatoid Arthritis patients from patients with other diseases such as hepatitis C infection. Rheumatoid Arthritis Classification Criteria include CCP IgG Antibody, rheumatoid factor, C-reactive protein and erythrocyte sedimentation rate (ESR). Approximately 70% of patients with Rheumatoid Arthritis are positive for Anti-CCP IgG, while only about 2% of random blood donors and disease controls subjects are positive.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153