|
|
| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Bile Acids Frac, Pregnancy 195
Test CodeBILEACID
Alias/See Also
BILEACID
CPT Codes
82542
Includes
Cholic Acid
Deoxycholic Acid
Chenodeoxycholic Acid
Total Bile Acids
Deoxycholic Acid
Chenodeoxycholic Acid
Total Bile Acids
Preferred Specimen
1 mL serum
Patient Preparation
Overnight fasting is preferred
Minimum Volume
1
Instructions
Overnight fasting best. Red top, pour off to transfer tube.
Transport Container
RED
Transport Temperature
T
Specimen Stability
Room temperature: 14 days
Refrigerated: 21 days
Frozen: 30 days
Refrigerated: 21 days
Frozen: 30 days
Methodology
Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Sun-Fri; Report available: 4-6 days
Reference Range
| Cholic Acid | ≤2.8 umol/L |
| Deoxycholic Acid | ≤2.3 umol/L |
| Chenodeoxycholic Acid | ≤3.9 umol/L |
| Total Bile Acids | ≤8.3 umol/L |
Clinical Significance
Intrahepatic cholestasis of pregnancy (ICP) is a rare disorder that typically occurs in the third trimester of pregnancy and is associated with itching, jaundice and disturbances in liver enzymes. While it poses little risk for the mother it may cause problems for the fetus, including preterm delivery, perinatal mortality and other disorders. Measurement of maternal serum bile acids can help in the diagnosis of ICP as the serum total bile acids are increased significantly (6-fold) with large increases primarily in cholic acid (12-fold).
Performing Laboratory
| Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
| 33608 Ortega Highway |
| San Juan Capistrano, CA 92675-2042 |
