Lysozyme Muramidase 619X

Test Code

LYSO

Alias/See Also

LYSO

CPT Codes
85549

Preferred Specimen

1 mL serum

Minimum Volume

Instructions

Draw one SST and send serum frozen

Transport Container

SST

Transport Temperature

Specimen Stability

Room temperature: 24 hours
Refrigerated: 15 days
Frozen: 18 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Room temperature samples older than 24 hours • Plasma collected in citrate or heparin • Moderate to gross hemolysis • Grossly lipemic

Methodology
Enzymatic

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Mon-Sat a.m.; Report available: Next day

Reference Range

5.0-11.0 mcg/mL

Clinical Significance

Lysozyme in the serum is primarily due to the degradation of granulocytes and monocytes and its concentration reflects the turnover of these cells. Increases are seen in benign and malignant processes. Serum lysozyme is elevated in patients with acute or chronic granulocytic or monocytic leukemias and levels decrease with successful treatment. Conversely, patients with lymphocytic leukemia may have depressed plasma lysozyme levels.

Performing Laboratory

Quest Diagnostics Nichols Institute

14225 Newbrook Drive

Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.