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| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
AFP Maternal Serum 5059
Test CodeAFP MAT SERUM
Alias/See Also
AFP MAT SERUM
CPT Codes
82105
Includes
AFP, Maternal Risk Interpretation
Preferred Specimen
1 mL serum collected in a serum separator tube (SST®)
Minimum Volume
1
Other Acceptable Specimens
Red-top tube (no gel)
Instructions
Enter all patient information. Specimen should be drawn between 14-22.9 wks gestation
Transport Container
SST
Transport Temperature
R
Specimen Stability
Room temperature: 14 days
Refrigerated: 14 days
Frozen: 45 days
Refrigerated: 14 days
Frozen: 45 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Grossly lipemic
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Mon-Sat; Report available: 3-5 days
Limitations
MSAFP results consistent with increased risk of NTD may be followed-up with appropriate diagnostic testing as detailed in the report. MSAFP does not screen for chromosomal abnormalities.
Reference Range
| AFP MoM: | |
| NTD | <2.50 |
| IDD | <1.90 |
| TWINS | <4.00 |
| TWINS IDD | <3.50 |
| TRIPLETS | <4.50 |
Clinical Significance
Maternal serum alpha-fetoprotein (MSAFP) is used for prenatal screening. Maternal serum Alpha-Fetoprotein (AFP) elevation is associated with open neural tube defects, multiple gestation, placental anomalies, ventral abdominal wall defects, congenital nephrosis, and oligohydramnios. Follow-up for abnormal AFP results include genetic counseling, level II or III ultrasound examination and consideration of amniocentesis for chromosome and AFP analysis. MSAFP is not to be used as a screening test for chromosomal abnormalities.
Performing Laboratory
| Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
| 33608 Ortega Highway |
| San Juan Capistrano, CA 92675-2042 |
