A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #

Porphyrins Frac Ur 24 Hr. 729X

Test Code
PQ


Alias/See Also
PQ


CPT Codes
84120

Includes
Coproporphyrin I & III: Heptacarboxyporphrin; Hexacarboxyporphyrin; Pentacarboxyporphyrin, Total porphyrins, Uroporphyrin I & III


Preferred Specimen
2 mL urine from a 24-hour urine collected in a 5 g sodium carbonate container or no preservative container - protected from light


Minimum Volume
1


Other Acceptable Specimens
No preservative - See Collection Instructions


Instructions
Protect from light while collecting. 24 Hr. Urine Send refrigerated


Transport Container
UJUG


Transport Temperature
R


Specimen Stability
Room temperature: Unacceptable
Refrigerated: 7 days
Frozen: 30 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature • Not protected from light • pH <4.0


Methodology
High Performance Liquid Chromatography (HPLC)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: Tues-Sat; Report available: 1-5 days


Reference Range
Uroporphyrin I 4.1-22.4 mcg/24 h
Uroporphyrin III 0.7-7.4 mcg/24 h
Heptacarboxyporphyrin ≤3.3 mcg/24 h
Hexacarboxyporphyrin ≤10 mcg/24 h
Pentacarboxyporphyrin ≤4.6 mcg/24 h
Coproporphyrin I 7.1-48.7 mcg/24 h
Coproporphyrin III 11.0-148.5 mcg/24 h
Total Porphyrins 35.0-210.7 mcg/24 h


Clinical Significance
Porphyria is a group of distinct disorders characterized by the abnormal accumulation of porphyrins or porphyrin precursors. Porphyrin Fractionation of Urine is useful in diagnosing porphyrin cutanea tarda, hereditary coproporphyria, and variegate porphyria.


Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.