Aldosterone/Renin Ratio 16845

Test Code
ALDREN

Alias/See Also
ALDREN

CPT Codes
82088;84244

Includes
Aldosterone, LC/MS and Plasma Renin Activity, LC/MS/MS

Preferred Specimen
1.8 mL frozen plasma collected in an EDTA (lavender-top) tube

Minimum Volume
1

Instructions
1.8 mL plasma from lavender EDTA, send frozen.

Transport Container
LAV

Transport Temperature
T

Specimen Stability
Room temperature: 24 hours
Refrigerated: 24 hours
Frozen: 28 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Plasma separator tube (PST)

Methodology
Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: Sun-Fri nights; Report available: 4-6 days

Reference Range
Aldosterone
Adult  
Upright 8:00-10:00 A.M. ≤28 ng/dL
Upright 4:00-6:00 P.M. ≤21 ng/dL
Supine 8:00-10:00 A.M. 3-16 ng/dL
Pediatric  
1-12 Months 2-70 ng/dL
1-4 Years 2-37 ng/dL
5-9 Years ≤9 ng/dL
10-13 Years ≤21 ng/dL
14-17 Years ≤35 ng/dL
Infants  
Premature (31-35 Weeks) ≤144 ng/dL
Term ≤217 ng/dL
Tanner Stages  
II-III Males 1-13 ng/dL
II-III Females 2-20 ng/dL
IV-V Males 3-14 ng/dL
IV-V Females 4-32 ng/dL

Plasma Renin Activity 0.25-5.82 ng/mL/h
Aldosterone/PRA Ratio 0.9-28.9 Ratio


Clinical Significance
The Aldosterone-renin ratio is used to screen for primary aldosteronism.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Dr
Chantilly, VA 20153



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.