Varicella Zoster IgG&IgM 34128X

Test Code
VZV PAN


Alias/See Also
VZV PAN


CPT Codes
86787 X 2

Includes
Chicken Pox


Preferred Specimen
1.5 mL serum


Minimum Volume
1


Instructions
Draw SST and send serum refrigerated


Transport Container
SST


Transport Temperature
R


Specimen Stability
Room temperature: 4 days
Refrigerated: 7 days
Frozen: 30 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Grossly icteric


Methodology
Immunoassay (IA)

Setup Schedule
Set up: Tues-Sat a.m.; Report available: Next day


Limitations
Other herpes viruses may cross react and produce high titers. Protection may be limited at low positive titers. Antibodies persist after infection has been treated or becomes dormant.


Reference Range
VZV Ab (IgG)
<135.00 Negative - Antibody not detected
135.00-164.99 Equivocal
≥165.00 Positive - Antibody detected
A positive result indicates that the patient has antibody to VZV but does not differentiate between an active or past infection. The clinical diagnosis must be interpreted in conjunction with the clinical signs and symptoms of the patient. This assay reliably measures immunity due to previous infection but may not be sensitive enough to detect antibodies induced by vaccination. Thus, a negative result in a vaccinated individual does not necessarily indicate susceptibility to VZV infection.
VZV Ab (IgM)
0.00-0.90 Negative
0.91-1.09 Equivocal
≥1.10 Positive


Clinical Significance
Varicella Zoster Virus (VZV) causes chickenpox and when
reactivated, potentially decades later,
causes shingles. Twenty percent of adults will develop
shingles, a rash or blister of the skin that may cause
severe pain.


Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.