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Cardiolipin AB, IGM 4663
Test CodeCARD-IGM
Alias/See Also
CARD-IGM
CPT Codes
8614791
Preferred Specimen
1 mL citrated plasma collected in a 3.2% sodium citrate (light blue-top) tube
Minimum Volume
1
Other Acceptable Specimens
1 mL serum
Instructions
Draw one SST and send serum refrigerated
Transport Container
SST
Transport Temperature
R
Specimen Stability
Room temperature: 5 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Tues-Sat; Report available: 3-5 days
Reference Range
| Value | Interpretation |
| <20.0 MPL-U/mL | Antibody not detected |
| ≥20.0 MPL-U/mL | Antibody detected |
Clinical Significance
Cardiolipin antibodies (CA) are seen in a subgroup of patients with autoimmune disorders, particularly Systemic Lupus Erythematosus (SLE), who are at risk for vascular thrombosis, thrombocytopenia, cerebral infarct and/or recurrent spontaneous abortion. Elevations of CA associated with increased risk have also been seen in idiopathic thrombocytopenic purpura, rheumatoid and psoriatic arthritis and primary Sjögren's syndrome.
Performing Laboratory
| Quest Diagnostics Nichols Institute |
| 14225 Newbrook Drive |
| Chantilly, VA 20153 |
