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Beta2 Glycoprotein I, IgG36554
Test CodeBETA2SER
Alias/See Also
BETA2SER
CPT Codes
86146
Preferred Specimen
1 mL plasma collected in a 3.2% sodium citrate (light blue-top) tube
Minimum Volume
1
Other Acceptable Specimens
1 mL serum
Instructions
1 mL serum from RED top, sent at room temp in plastic vial.
Transport Container
Serum in plastic screw cap vial
Transport Temperature
T
Specimen Stability
Room temperature: 5 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Mon-Sat; Report available: 3-4 days
Limitations
Factor VIII inhibitors may cause a false-positive lupus anticoagulation test. The temporary presence of antiphospholipid antibodies may accompany infections or certain drugs.
Reference Range
Value | Interpretation |
<20 U/mL | Antibody not detected |
≥20 U/mL | Antibody detected |
Clinical Significance
Beta-2-Glycoprotein 1, apolipoprotein H, is a cofactor in antiphospholipid antibody binding and is the critical antigen in the antiphospholipid antibody syndrome. Beta-2- Glycoprotein 1 antibody is more specific than cardiolipin antibody that may express reactivity in patients with syphilis and other infectious diseases.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153