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C-Peptide Serum 372
Test CodeC PEP
Alias/See Also
C PEP
CPT Codes
84681
Preferred Specimen
1 mL serum
Patient Preparation
Patients should fast 12 hours prior to collection.
Minimum Volume
1
Instructions
Draw one SST and send serum frozen
Transport Container
SST
Transport Temperature
F
Specimen Stability
Room temperature: 4 days
Refrigerated: 7 days
Frozen: 7 days
Refrigerated: 7 days
Frozen: 7 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Plasma • Gross hemolysis
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Mon-Sat a.m.; Report available: Next day
Reference Range
0.80-3.85 ng/mL
Clinical Significance
C-Peptide is useful in the evaluation of pancreatic beta cell function (e.g., helping distinguish type 1 from type 2 diabetes mellitus, or monitoring patients who have received islet cell or pancreatic transplants) and for determining the source of insulin in patients with hyperinsulinemic hypoglycemia (e.g., distinguishing insulin-secreting tumors from exogenous insulin administration). It is also sometimes measured as an additional means (more resistant to hemolysis than is insulin itself) for evaluating glucose tolerance tests.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153