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Vitamin C, LC/MS/MS 929
Test CodeVITC
Alias/See Also
VITC
CPT Codes
82180
Preferred Specimen
1 mL frozen serum - protected from light
Patient Preparation
Overnight fasting is preferred. Refrain from eating fuits and from taking Vitamin C supplements 24 hours prior collection.
Minimum Volume
1
Other Acceptable Specimens
Plasma collected in sodium heparin (green-top) tube - protected from light
Instructions
Fasting specimen. Diet restrictions. Protect light send froz. SST
Transport Container
SST
Transport Temperature
F
Specimen Stability
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen (-20°C): 8 hours
Frozen (-70°C): 35 days
Refrigerated: Unacceptable
Frozen (-20°C): 8 hours
Frozen (-70°C): 35 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Not light protected • EDTA plasma • Lithium heparin plasma • Thawed samples • Lipemic • Hemolysis • Received room temperature • Received refrigerated
Methodology
Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Tues-Sat; Report available: 4-5 days
Reference Range
| Female | 0.3-2.7 mg/dL |
| Male | 0.2-2.1 mg/dL |
Clinical Significance
Vitamin C is an antioxidant involved in connective tissue metabolism, drug-metabolizing systems, and mixed-function oxidase systems to list a few. Vitamin C deficiency causes scurvy; manifestations include impaired formation of mature connective tissue, bleeding into the skin, weakness, fatigue, and depression.
Performing Laboratory
Quest Diagnostics Nichols Institute Valencia
27027 Tourney Road
Valencia, CA 91355-5386
