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Gabepentin 3557
Test CodeGABAP
Alias/See Also
GABAP
CPT Codes
80171
Preferred Specimen
1 mL serum collected in a red-top tube (no gel)
Patient Preparation
Draw sample 2 hours after last dose
Minimum Volume
1
Other Acceptable Specimens
Plasma collected in: EDTA (lavender-top), sodium heparin (green-top), or lithium heparin (green-top) tube
Instructions
Draw specimen 2 hours after dose. Separate plasma ASAP Send refrigerated
Transport Container
LAV
Transport Temperature
R
Specimen Stability
Room temperature: 5 days
Refrigerated: 12 days
Frozen: 30 days
Refrigerated: 12 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gel barrier/Serum Separator Tube (SST®) • Gross hemolysis
Methodology
Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Mon-Sat a.m.; Report available: Next day
Reference Range
2.7-4.1: (peak) following a single dose of 900-1800 mg/day.
4.0-8.5: (peak) following a multiple dose of 900-1800 mg/day administration.
The reference range is evolving. Seizure control has been observed at levels in excess of 4 mcg/mL.
4.0-8.5: (peak) following a multiple dose of 900-1800 mg/day administration.
The reference range is evolving. Seizure control has been observed at levels in excess of 4 mcg/mL.
Clinical Significance
Gabapentin is an anticonvulsant drug commonly used as adjunctive therapy to treat partial seizures. Therapeutic drug monitoring is useful to optimize dose and to avoid toxicity.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153
