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Imipramine Desipramine 887X

Test Code
TFR


Alias/See Also
TFR


CPT Codes
80335

Includes
Imipramine, Desipramine and Total


Preferred Specimen
3 mL serum collected in a red-top tube (no gel)


Minimum Volume
1


Other Acceptable Specimens
Plasma collected in: EDTA (lavender-top), sodium heparin (green-top), or lithium heparin (green-top) tube


Instructions
Draw red top (no gel) send serum room temperature. Draw 12 hours after dose.


Transport Container
RED


Transport Temperature
T


Specimen Stability
Room temperature: 5 days
Refrigerated: 5 days
Frozen: 30 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Gel barrier/Serum separator tube (SST)


Methodology
Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: Mon-Sat; Report available: 1-2 days


Reference Range
Total 150-250 mcg/L


Clinical Significance
Imipramine is a tricyclic antidepressant drug used to treat depression. Therapeutic drug monitoring is used to optimize dose and to avoid toxicity.


Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.