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| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
TICKAB PAN
Test CodeTICKAB PAN
CPT Codes
86618, 86666 (x4), 86753 (x2)
Includes
Lyme Disease Antibody with Reflex to Immunoassay (IgG, IgM) (MTTT)
Anaplasma phagocytophilum Antibodies (IgG, IgM) with Reflex to Titer
Babesia microti Antibodies (IgG, IgM) with Reflex to Titers
Ehrlichia chaffeensis Antibodies (IgG, IgM) with Reflex to Titers
If Lyme Disease Antibody is Positive or Equivocal (≥0.90), then Lyme Disease Supplemental Antibodies (IgG, IgM), Immunoassay will be performed at an additional charge (CPT code(s): 86617(x2)).
If A. phagocytophilum (IgG) is Detected, then A. phagocytophilum (IgG) Titer will be performed at an additional charge (CPT code(s): 86317).
If A. phagocytophilum (IgM) is Detected, then A. phagocytophilum (IgM) Titer will be performed at an additional charge (CPT code(s): 86317).
If Babesia microti (IgG) is Detected, then Babesia microti (IgG) Titer will be performed at an additional charge (CPT code(s): 86317).
If Babesia microti (IgM) is Detected, then Babesia microti (IgM) Titer will be performed at an additional charge (CPT code(s): 86317).
If E. chaffeensis (IgG) is Detected, then E. chaffeensis (IgG) Titer will be performed at an additional charge (CPT code(s): 86317).
If E. chaffeensis (IgM) is Detected, then E. chaffeensis (IgM) Titer will be performed at an additional charge (CPT code(s): 86317).
Anaplasma phagocytophilum Antibodies (IgG, IgM) with Reflex to Titer
Babesia microti Antibodies (IgG, IgM) with Reflex to Titers
Ehrlichia chaffeensis Antibodies (IgG, IgM) with Reflex to Titers
If Lyme Disease Antibody is Positive or Equivocal (≥0.90), then Lyme Disease Supplemental Antibodies (IgG, IgM), Immunoassay will be performed at an additional charge (CPT code(s): 86617(x2)).
If A. phagocytophilum (IgG) is Detected, then A. phagocytophilum (IgG) Titer will be performed at an additional charge (CPT code(s): 86317).
If A. phagocytophilum (IgM) is Detected, then A. phagocytophilum (IgM) Titer will be performed at an additional charge (CPT code(s): 86317).
If Babesia microti (IgG) is Detected, then Babesia microti (IgG) Titer will be performed at an additional charge (CPT code(s): 86317).
If Babesia microti (IgM) is Detected, then Babesia microti (IgM) Titer will be performed at an additional charge (CPT code(s): 86317).
If E. chaffeensis (IgG) is Detected, then E. chaffeensis (IgG) Titer will be performed at an additional charge (CPT code(s): 86317).
If E. chaffeensis (IgM) is Detected, then E. chaffeensis (IgM) Titer will be performed at an additional charge (CPT code(s): 86317).
Preferred Specimen
2 mL serum
Minimum Volume
1.5 mL
Transport Container
Transport tube
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 72 hours
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days
Methodology
See individual tests
Setup Schedule
Set up and Report available: See individual tests
Reference Range
| Lyme Ab, Screen | <0.90 index |
| A. phagocytophilum Ab (IgG), Screen | Not Detected |
| A. phagocytophilum Ab (IgM), Screen | Not Detected |
| Babesia microti Ab (IgG), Screen | Not Detected |
| Babesia microti Ab (IgM), Screen | Not Detected |
| E. chaffeensis Ab (IgG), Screen | Not Detected |
| E. chaffeensis Ab (IgM), Screen | Not Detected |
| Lyme Ab (IgG) | <0.90 index |
| Lyme Ab (IgM) | <0.90 index |
| A. phagocytophilum Ab (IgG), Titer | <1:64 titer |
| A. phagocytophilum Ab (IgM), Titer | <1:20 titer |
| Babesia microti Ab (IgG), Titer | <1:64 titer |
| Babesia microti Ab (IgM), Titer | <1:20 titer |
| E. chaffeensis Ab (IgG), Titer | <1:64 titer |
| E. chaffeensis Ab (IgM), Titer | <1:20 titer |
Clinical Significance
This panel contains components for the detection of antibodies against Borrelia burgdorferi (Lyme disease) using the modified two-tier algorithm, Anaplasma phagocytophilum, Ehrlichia chaffeensis, and Babesia microti. Infection with these organisms can occur from the bite of a tick found in endemic regions, including the upper Northeast and Midwestern United States. Appropriate reflex testing of individual components is performed for initial screen results.
The tests included in the panel are serologic assays used to aid in the diagnosis of select tickborne related illnesses. Testing for tickborne diseases is based on a clinical evaluation and risk of tick exposure with consideration to the geographic region of potential exposure. Symptoms may be nonspecific, including fever/chills, muscle aches, fatigue, and rash. Although infections may have a distinctive rash, some may be undifferentiated or atypical. These infections often have overlapping vectors, geographic endemicity, and similar clinical signs and symptoms. In some cases, co-infection can occur. Therefore, it is suggested that testing for multiple pathogens in the same endemic region be considered.
Testing of IgG and IgM are included for individual components. Negative results can occur early in infection. Seroconversion or a four-fold increase between acute and convalescent sera can be used to support a diagnosis. The presence of IgG alone may indicate past infection and IgM in some cases may persist for many months after infection has resolved. Cross-reactivity between related organisms, such as Anaplasma and Ehrlichia, can occur. Therefore, interpretation of serologic results is done in the context of pertinent clinical picture, including timing from symptom onset.
The tests included in the panel are serologic assays used to aid in the diagnosis of select tickborne related illnesses. Testing for tickborne diseases is based on a clinical evaluation and risk of tick exposure with consideration to the geographic region of potential exposure. Symptoms may be nonspecific, including fever/chills, muscle aches, fatigue, and rash. Although infections may have a distinctive rash, some may be undifferentiated or atypical. These infections often have overlapping vectors, geographic endemicity, and similar clinical signs and symptoms. In some cases, co-infection can occur. Therefore, it is suggested that testing for multiple pathogens in the same endemic region be considered.
Testing of IgG and IgM are included for individual components. Negative results can occur early in infection. Seroconversion or a four-fold increase between acute and convalescent sera can be used to support a diagnosis. The presence of IgG alone may indicate past infection and IgM in some cases may persist for many months after infection has resolved. Cross-reactivity between related organisms, such as Anaplasma and Ehrlichia, can occur. Therefore, interpretation of serologic results is done in the context of pertinent clinical picture, including timing from symptom onset.
Performing Laboratory
| Quest Diagnostics Nichols Institute |
| 14225 Newbrook Drive |
| Chantilly, VA 20153 |
