Myeloproliferative Neoplasms(MPN) for Eosinophilia, FISH

Message
Submit 1 of the following specimens following standard collection procedures: Blood collected in a Green NaHep tube. Bone marrow collected in a Green NaHep tube. Fresh tissue collected in transport media or formalin-fixed paraffin- embedded tissue block


Test Code
LAB17025 MPNEF


Alias/See Also
MPNEF


CPT Codes
88271| 88275

Includes
Clinical history and reason for referral are required with test order. Prior therapy and bone marrow transplant history should be provided with test order.Note: For each probe set in the panel, 100-300 interphase cells are microscopically analyzed for probe signal patterns indicating rearrangement of the regions: PDGFRA at band 4q12; PDGFRB at band 5q33.1; and FGFR1 at band 8p11-12.If results are not possible, the test order may be canceled and replaced with a Cytogenetics Communication.@BKRCERMSGREFRESH(2302793)@ @BKRCERMSGREFRESH(2302794)@


Instructions
Processing Instructions (Lab use only): Specimen viability decreases during transit. Send specimen to testing laboratory for viability determination. Send original tube. Do not freeze. Do not reject. Minimum Testing Volume: 5mm x 5mm Fresh tissue3.0 mL Whole blood1.0 mL Bone marrow Transport Temperature: Ambient Stability: Ambient: Testing laboratory determines Refrigerated : Testing laboratory determines Frozen: N/A


Report Available
6-Days


Clinical Significance
1230171323



Last Updated: May 18, 2026


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.