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CSF 14-3-3 Protein (Prion Disease)
MessagePatient Preparation: Cerebrospinal Fluid (CSF) obtained by lumbar puncture. The first 2 mL of CSF that flows from the tap should be discarded. Collect 2 mL of CSF (1 mL minimum), avoiding bloody tap. The sample must be immediately frozen, at least in a -20° C freezer. Freeze within 20 minutes of collection. Store and transport frozen. Required patient information: Please complete and send the National Prion Requisition "Test Request Form", available on the website at National Prion Disease Pathology Surveillance Center with the sample. CSF Test RequisitionImmediate Specimen Processing: Freeze within 20 minutes of collection. Ambulatory Transport Temperature to Inova Central Lab: FrozenSpecimen Stability: Indefinitely
Test Code
LAB17688 1433P
Alias/See Also
1433P
CPT Codes
0035U| 83520| 84394
Includes
Patient Preparation: The patient must be 12 years of age or older.This test includes the following components: 14-3-3 GAMMA, T-tau protein, and RT-QuIC@BKRCERMSGREFRESH(2302793)@ @BKRCERMSGREFRESH(2302794)@
Instructions
Processing Instructions: Specimen must remain frozen. Ship to Quest frozen. Required patient information: Please complete and send the National Prion Requisition "Test Request Form", available on the website at National Prion Disease Pathology Surveillance Center with the sample.CSF Test RequisitionPreferred Testing Volume: 2 mL CSFMinimum Testing Volume: 1 mL CSF Transport Temperature: Frozen Stability: Ambient: UnacceptableRefrigerated : UnacceptableFrozen: Indefinitely Causes for Rejection: Bloody and insufficient sample quantity. Samples that are colored or contain blood cannot be performed for RT-QuIC and 14-3-3 GAMMA.Performing Lab: Performing Lab: National Prion Disease Pathology Surveillance Center
Report Available
9-Days
Clinical Significance
1230171455
Last Updated: May 18, 2026
