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ANA Screen w/Reflex

Message
If ANA is positive or equivocal, the following autoantibody markers will be reflexed and reported as a quantitative result in U/mL:
ADNA -- anti-double stranded DNA
SSARO – SS-A (Sjogren’s) antibody
SSBLA – SS-B (Sjogren’s) antibody
SM -- SM (Smith) antibody
RNP     -- RNP antibody
SCL     -- SCL-70 (Scleroderma) antibody
JO1      -- JO-1 antibody
CENT  -- Centromere antibody
HIST   --  Histone antibody



Test Code
Lab147


Alias/See Also
Anti-Nuclear ABY Screen / RFLX
ANAQ


CPT Codes
86038

Preferred Specimen
Serum


Minimum Volume
1 mL


Instructions
Centrifuge SST after clotting to separate serum from cells


Transport Container
Serum Separator Tube (SST)


Transport Temperature
Refrigerated


Specimen Stability
Refrigerated – 7 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Storage and stability requirements not met
Improper or no label on container
Improper container
Leaking container
Quantity not sufficient
Expired collection tube


Methodology
Athena

Setup Schedule
Monday-Friday


Reference Range
Positive > 120 AU/mL
Equivocal 100-120 AU/mL
Non-Reactive  <100 AU/mL



Clinical Significance
Meritus Medical Laboratory’s ANA screen with reflex to individual autoantibodies is designed to aid in the diagnosis of many of the systemic autoimmune disorders.  It may assist in the detection and identification of many autoantibodies to a number of nuclear and cytoplasmic cellular constituents.  Some of the most common examples of systemic autoimmune disease are systemic lupus erythematosus (SLE), rheumatoid arthritis, scleroderma (and CREST), polymyositis, mixed connective tissue disease (MCTD), drug-induced SLE and Sjögren’s Syndrome.


Performing Laboratory
Meritus Immunology - Microbiology



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.