Vitamin E (Tocopherol)

Test Code

CPT Codes

Alpha-Tocopherol, Beta-Gamma-Tocopherol

Preferred Specimen
2 mL serum - protect from light

Minimum Volume
0.7 mL

Separate from cells as soon as possible after clotting. Send serum in an amber tube. If amber tube is not available, wrap tube in aluminum foil to protect from light.

Transport Container
Plastic screw-cap vial protected from light

Transport Temperature
Refrigerated (cold packs)

Specimen Stability
Room temperature: 24 hours
Refrigerated: 7 days
Frozen: 28 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Room temperature • Not protected from light (room temperature and refrigerated)

High Performance Liquid Chromatography (HPLC)

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range
Adult 5.7-19.9 mg/L
  Term Infants (Cord Blood) 1.8-5.8 mg/L
  4 Months-1 Year ≤9.1 mg/L
  1-2 Years 2.9-16.6 mg/L
  3-5 Years 5.5-11.8 mg/L
  6-8 Years 4.6-14.8 mg/L
  9-11 Years 6.2-14.3 mg/L
  12-17 Years 3.7-12.4 mg/L

Adult ≤4.3 mg/L
Pediatric 3-17 Years ≤3.8 mg/L

Clinical Significance
Deficiency of vitamin E may cause extensive neuropathy in young children and, in addition, is suspect as a possible cause of motor and sensory neuropathy in older children and in adults. One likely cause of vitamin E deficiency is intestinal malabsorption, resulting from bowel disease, pancreatic disease, or chronic cholestasis. Other causes of malabsorption of vitamin E include celiac disease, cystic fibrosis, and intestinal lymphangiectasia.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.